Methylene Blue or METYLENE BLUE 1000mg.
Purity ≥ 99.99%
- Pharmaceutical Quality / UPS PHARMA GRADE.
Net weight: 1000mg
Cas Number: 61-73-4
Molecular formula: C16H18ClN3S
Molecular weight: 319.85 g-mol-1
Packaging: sealed aluminum sachet.
- Intended use: For lab testing only not for consumption!
Description translated from English Wikipedia:
Methylthionine chloride, also commonly known as methylene blue, is a salt used as a dye and as a drug.
Methylene blue is a thiazine dye. As a drug, it is mainly used to treat methemoglobinemia by converting ferrous iron in hemoglobin into ferrous iron. In particular, it is used to treat methemoglobin levels that exceed 30% or where symptoms are present despite oxygen therapy. It was previously used for cyanide poisoning and urinary tract infections, but this use is no longer recommended.
Methylene blue is usually administered by injection into the bloodstream. Common side effects include headache, vomiting, confusion, shortness of breath and high blood pressure. Other side effects include serotonin syndrome, red blood cell breakdown and allergic reactions. Use often changes the color of urine, sweat and stool from blue to green. Although use during pregnancy can harm the baby, not using it in methemoglobinemia is probably more dangerous.
Methylene blue was first prepared in 1876 by Heinrich Caro. It is on the World Health Organization’s list of essential medicines.
Methylene blue is used as a drug to treat methemoglobinemia, which can result from the ingestion of certain drugs, toxins or beans. Normally, through the enzymes NADH- or NADPH-dependent methemoglobin reductase, methemoglobin is reduced back to hemoglobin. When large amounts of methemoglobin occur secondary to toxins, methemoglobin reductases are overwhelmed. Methylene blue, when injected intravenously as an antidote, is first reduced to leucoethylene blue, which then reduces the heme group from methemoglobin to hemoglobin. Methylene blue can shorten the half-life of methemoglobin from hours to minutes.However, in high doses, methylene blue actually induces methemoglobinemia, reversing this pathway.
Hyoscyamine / hexamethylenetetramine / phenyl salicylate / methylene blue / benzoic acid (trade names Methylphen, Prosed DS) is a drug combination. It is not safe or effective for any medical purpose.
Because its reduction potential is similar to that of oxygen and can be reduced by components of the electron transport chain, large doses of methylene blue are sometimes used as an antidote to potassium cyanide poisoning, a method first tested successfully in 1933 by Dr. Matilda Moldenhauer Brooks in San Francisco, although first demonstrated by Bo Sahlin of Lund University, in 1926.